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If feasible, gamma knife radiosurgery is the treatment of choice for Nelson corticotroph tumors. There are also lateral displacements of the chiasm, which may cause either its right or its left branch to lie above the diaphragma. Osmoreceptors continuously monitor plasma osmolality. Persons with central DI typically have a sudden onset of polyuria and thirst for cold liquids. The rapid expansion of the sellar contents results in the immediate mass-effect symptoms.
